Phenylketonuria (PKU) is an example of: MCQ with Answer and Explanation

Phenylketonuria (PKU) is an example of:
A. Sex-linked inheritance
B. Pleiotropy
C. Polygenic inheritance
D. Epistasis
Answer: Option B
Solution (By JKSSB Mock Tests)
Pleiotropy is a phenomenon where a single gene influences multiple, seemingly unrelated phenotypic traits. Phenylketonuria (PKU) is an autosomal recessive metabolic disorder caused by a mutation in a single gene (PAH) that codes for the enzyme phenylalanine hydroxylase. This single mutation leads to multiple effects: intellectual disability, reduced hair and skin pigmentation, and musty odor.

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Practice More Biology Questions

Question #1
Which of the following is a correct statement about viruses?
A. They are living organisms that can reproduce outside a host.
B. They are obligate intracellular parasites.
C. They have cell walls like bacteria.
D. They contain both DNA and RNA.

Correct Answer: Option B


Explanation:
Viruses are non-living outside a host cell and must hijack a host's cellular machinery to replicate, making them obligate intracellular parasites. They contain either DNA or RNA, not both (except some rare cases). They lack cell walls and metabolic machinery. Their status as living or non-living is debated, but they are biologically active only inside a host.

This question belongs to: Science Biology
Question #2
The 'Urey-Miller experiment' simulated the conditions of early Earth to demonstrate the synthesis of:
A. Amino acids
B. DNA
C. Lipids
D. Proteins

Correct Answer: Option A


Explanation:
Stanley Miller and Harold Urey (1953) simulated primitive Earth conditions by mixing methane, ammonia, hydrogen, and water vapor and providing electric discharge (simulating lightning). They obtained amino acids (glycine, alanine, etc.), supporting the chemical origin of life hypothesis. It didn't produce proteins, DNA, or lipids directly. This experiment was crucial for abiogenesis theories.

This question belongs to: Science Biology
Question #3
Consider statements about human digestion: 1. Pepsin digests proteins in the stomach. 2. Trypsin is secreted by the liver. 3. Lipase emulsifies fats. Which are correct?
A. 1 and 3 only
B. 2 and 3 only
C. 1, 2 and 3
D. 1 only

Correct Answer: Option D


Explanation:
Pepsin is the primary proteolytic enzyme in the stomach, breaking down proteins into peptones. Trypsin is a pancreatic enzyme secreted by the pancreas, not the liver, which continues protein digestion in the small intestine. Bile, produced by the liver, emulsifies fats, but lipase (pancreatic lipase) actually digests (hydrolyzes) them into fatty acids and glycerol. Only statement 1 is correct.

This question belongs to: Science Biology