The neurotransmitter that is deficient in Parkinson's disease is: MCQ with Answer and Explanation

The neurotransmitter that is deficient in Parkinson's disease is:
A. Serotonin
B. Norepinephrine
C. Dopamine
D. Acetylcholine
Answer: Option C
Solution (By JKSSB Mock Tests)
Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopamine-producing neurons in the substantia nigra region of the brain. This leads to motor symptoms like tremors, rigidity, and bradykinesia. L-DOPA (levodopa), a precursor of dopamine, is used in treatment. Acetylcholine is related to Alzheimer's, serotonin to depression.

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Practice More Biology Questions

Question #1
The scientist who first successfully synthesized the gene for somatostatin (a hormone) in a bacterium, demonstrating the potential of recombinant DNA technology for producing human hormones, was:
A. Paul Berg
B. Keiichi Itakura
C. Herbert Boyer and Stanley Cohen
D. Arthur Kornberg

Correct Answer: Option B


Explanation:
In 1977, Keiichi Itakura and his colleagues at the City of Hope National Medical Center, in collaboration with Herbert Boyer's lab, successfully synthesized the gene for somatostatin (a hypothalamic hormone) and inserted it into E. coli. The bacteria then produced the somatostatin protein. This was a landmark achievement, as it was the first time a synthetic human gene was expressed in a bacterium to produce a functional human hormone, paving the way for the commercial production of insulin and other therapeutics.

This question belongs to: Science Biology
Question #2
Consider statements about human physiology: 1. The liver stores glycogen. 2. The spleen filters blood and removes old RBCs. 3. The appendix is essential for digestion. Which are correct?
A. 2 and 3 only
B. 1 and 3 only
C. 1 and 2 only
D. 1, 2 and 3

Correct Answer: Option C


Explanation:
The liver plays a crucial role in carbohydrate metabolism, storing excess glucose as glycogen and releasing it when blood sugar drops. The spleen acts as a blood filter, removing old, damaged, or abnormal red blood cells and storing platelets. The appendix is a small, blind-ended tube attached to the cecum; it has no significant role in human digestion and is considered a vestigial organ. Thus, statements 1 and 2 are correct.

This question belongs to: Science Biology
Question #3
Assertion (A): Genetic variation is essential for evolution.
Reason (R): Without variation, natural selection cannot occur because there are no differences to select from.
A. A true, R false.
B. A false, R true.
C. Both A and R are true, but R is not the correct explanation.
D. Both A and R are true, and R is the correct explanation.

Correct Answer: Option D


Explanation:
Genetic variation provides the raw material for natural selection. If all individuals were identical, selection could not favor any. R correctly explains A.

This question belongs to: Science Biology