In biotechnology, the 'PCR' (Polymerase Chain Reaction) technique requires a thermostable DNA polymerase. The most commonly used enzyme for this is: MCQ with Answer and Explanation

In biotechnology, the 'PCR' (Polymerase Chain Reaction) technique requires a thermostable DNA polymerase. The most commonly used enzyme for this is:
A. Reverse transcriptase
B. Taq polymerase
C. T7 polymerase
D. DNA polymerase I
Answer: Option B
Solution (By JKSSB Mock Tests)
PCR involves repeated cycles of high-temperature denaturation (around 94°C) to separate the DNA strands. Normal DNA polymerases would be destroyed at these temperatures. Therefore, a thermostable DNA polymerase is required. Taq polymerase, isolated from the thermophilic bacterium Thermus aquaticus found in hot springs, is the most commonly used enzyme because it can withstand the high denaturation temperatures without losing its activity, eliminating the need to add fresh enzyme after each cycle.

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