In the human respiratory system, the 'Surfactant' is a lipoprotein complex secreted by which cells to reduce surface tension in the alveoli? MCQ with Answer and Explanation

In the human respiratory system, the 'Surfactant' is a lipoprotein complex secreted by which cells to reduce surface tension in the alveoli?
A. Goblet cells
B. Alveolar macrophages
C. Type I alveolar cells
D. Type II alveolar cells
Answer: Option D
Solution (By JKSSB Mock Tests)
Pulmonary surfactant is a complex mixture of lipids (primarily dipalmitoylphosphatidylcholine) and proteins secreted by Type II alveolar cells (septal cells) in the lungs. Its primary function is to reduce the surface tension of the fluid lining the alveoli. Without surfactant, the alveoli would collapse at the end of expiration (atelectasis) due to high surface tension, making it extremely difficult to re-inflate the lungs during inspiration.

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Question #1
The disease 'pellagra' is caused by the deficiency of:
A. Vitamin B₁ (Thiamine)
B. Vitamin B₆ (Pyridoxine)
C. Vitamin B₂ (Riboflavin)
D. Vitamin B₃ (Niacin)

Correct Answer: Option D


Explanation:
Pellagra, characterized by dermatitis, diarrhea, and dementia (3 Ds), is caused by a deficiency of niacin (vitamin B₃) or its precursor tryptophan. It is common in populations with corn-based diets lacking tryptophan. Beriberi is due to B₁ deficiency, cheilosis to B₂, peripheral neuropathy to B₆. Niacin is a component of coenzymes NAD and NADP.

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Question #2
The infective stage of the malarial parasite in humans is:
A. Sporozoite
B. Gametocyte
C. Trophozoite
D. Merozoite

Correct Answer: Option A


Explanation:
The sporozoite is the motile infective stage injected by the female Anopheles mosquito into the human host. It invades liver cells. Gametocytes are the stage taken up by the mosquito, merozoites are released from liver and infect RBCs.

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Question #3
Erythroblastosis fetalis is a severe condition caused by the incompatibility of blood groups between the mother and fetus, specifically involving the:
A. Rh factor (Rhesus factor)
B. ABO blood group system
C. Kell antigen
D. Duffy antigen

Correct Answer: Option A


Explanation:
Erythroblastosis fetalis (hemolytic disease of the newborn) is primarily caused by Rh incompatibility. It occurs when an Rh-negative mother carries an Rh-positive fetus. During the first pregnancy, fetal Rh+ red blood cells may enter the mother's circulation, prompting her to produce anti-Rh antibodies. In subsequent pregnancies with an Rh+ fetus, these antibodies cross the placenta and destroy the fetal red blood cells, causing severe anemia and jaundice.

This question belongs to: Science Biology