The disease caused by the variant Creutzfeldt-Jakob disease is linked to: MCQ with Answer and Explanation

The disease caused by the variant Creutzfeldt-Jakob disease is linked to:
A. Bacteria
B. Fungus
C. Virus
D. Prion
Answer: Option D
Solution (By JKSSB Mock Tests)
Variant CJD is a fatal prion disease linked to consumption of beef from cattle with bovine spongiform encephalopathy (mad cow disease). Prions are misfolded proteins that induce other proteins to misfold. Not viral, bacterial, or fungal.

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Practice More Biology Questions

Question #1
Which of the following is a correct statement about mitochondria?
A. They are single-membrane organelles.
B. They are found in both prokaryotes and eukaryotes.
C. They have their own circular DNA.
D. They contain 80S ribosomes.

Correct Answer: Option C


Explanation:
Mitochondria are double-membrane organelles with circular DNA (like prokaryotes) and 70S ribosomes, supporting the endosymbiotic origin. They are absent in prokaryotes. They are the site of aerobic respiration. The matrix contains enzymes for Krebs cycle. The inner membrane forms cristae, housing electron transport chain and ATP synthase.

This question belongs to: Science Biology
Question #2
Consider statements about photosynthesis: 1. Light reactions occur in the grana. 2. The Calvin cycle occurs in the stroma. 3. Oxygen is released from CO2. Which are correct?
A. 1, 2 and 3
B. 2 and 3 only
C. 1 and 2 only
D. 1 and 3 only

Correct Answer: Option C


Explanation:
Photosynthesis consists of light-dependent reactions occurring in the thylakoid membranes (grana) where water is split, releasing oxygen, and light-independent reactions (Calvin cycle) occurring in the stroma where CO2 is fixed. The oxygen released during photosynthesis comes from the photolysis of water, not from carbon dioxide. Thus, statements 1 and 2 are correct.

This question belongs to: Science Biology
Question #3
The 'pUC19' plasmid is a widely used cloning vector. A key feature of pUC19 that facilitates the selection of recombinant clones is the presence of:
A. The rop gene for replication control
B. Genes for nitrogen fixation
C. Multiple origins of replication
D. The lacZ gene for alpha-complementation (blue-white screening)

Correct Answer: Option D


Explanation:
pUC19 is a small, high-copy-number cloning vector. A crucial feature for selecting recombinant clones is the presence of the lacZ' gene, which codes for the alpha-peptide of beta-galactosidase. The multiple cloning site (MCS) is located within this lacZ' gene. When foreign DNA is inserted into the MCS, it disrupts the lacZ' gene (insertional inactivation). On media containing X-gal and IPTG, colonies with empty vectors turn blue, while colonies with recombinant plasmids (disrupted lacZ') remain white, allowing easy visual selection.

This question belongs to: Science Biology