The 'Hormone Adrenocorticotropic Hormone' (ACTH) is secreted by the anterior pituitary. Its primary target and function are: MCQ with Answer and Explanation

The 'Hormone Adrenocorticotropic Hormone' (ACTH) is secreted by the anterior pituitary. Its primary target and function are:
A. The adrenal cortex; stimulating the production and release of glucocorticoids (primarily cortisol)
B. The adrenal medulla; stimulating adrenaline release
C. The thyroid gland; stimulating thyroid hormone release
D. The gonads; stimulating sex hormone production
Answer: Option A
Solution (By JKSSB Mock Tests)
Adrenocorticotropic Hormone (ACTH) is a peptide hormone secreted by the corticotroph cells of the anterior pituitary gland. Its primary target is the adrenal cortex (the outer layer of the adrenal glands). ACTH stimulates the growth of the adrenal cortex and the synthesis and secretion of its steroid hormones, primarily the glucocorticoids (like cortisol), and to a lesser extent, androgens and mineralocorticoids. ACTH secretion is controlled by Corticotropin-Releasing Hormone (CRH) from the hypothalamus and by the negative feedback of cortisol.

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Which of the following is the primary target organ for the hormone insulin?
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Correct Answer: Option C


Explanation:
Insulin acts primarily on liver, muscle, and adipose tissue. The liver is a key target where insulin promotes glycogenesis (glucose to glycogen), glycolysis, and lipogenesis, and inhibits gluconeogenesis, lowering blood glucose. Muscle and adipose tissue also respond. Brain takes up glucose independently of insulin via GLUT1 transporters. Thus liver is a principal target.

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C. Benign tumor growth
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Correct Answer: Option A


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Metastasis is the process by which malignant cancer cells detach from the primary tumor, travel through the blood or lymph, and establish secondary tumors in other organs. Benign tumors do not metastasize. Apoptosis is programmed cell death.

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Consider the following statements about the immune system:
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