The 'Hormone Leptin' acts on the hypothalamus to regulate energy balance. It does this primarily by binding to receptors in the: MCQ with Answer and Explanation

Leptin is a hormone secreted by adipose tissue that signals the status of body fat stores to the brain. It acts primarily on the arcuate nucleus (ARC) of the hypothalamus. The ARC contains two key populations of neurons: one that co-expresses Neuropeptide Y (NPY) and Agouti-related peptide (AgRP), which stimulate appetite, and another that expresses Pro-opiomelanocortin (POMC) and Cocaine- and amphetamine-regulated transcript (CART), which suppress appetite. Leptin binds to receptors on these neurons, inhibiting the NPY/AgRP neurons and stimulating the POMC/CART neurons, thereby reducing appetite and increasing energy expenditure.