The 'Hormone Neurotensin' is a peptide found in the central nervous system and the gastrointestinal tract. In the gut, its primary functions include:
A. Increasing intestinal absorption of water
B. Stimulating insulin release
C. Inhibiting gastric motility and acid secretion, and stimulating the release of histamine and glucagon
D. Stimulating gastric acid secretion
Answer: Option C
Solution (By JKSSB Mock Tests)
Neurotensin is a 13-amino acid peptide that functions as both a neuromodulator in the central nervous system and a hormone in the gastrointestinal tract. In the gut, it is secreted by the N cells in the ileum in response to fat ingestion. Its primary gastrointestinal functions are to inhibit gastric motility and gastric acid secretion (contributing to the 'ileal brake'), and to stimulate the release of histamine from mast cells and glucagon from the pancreas. It also causes vasodilation in the intestinal mucosa.
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