The 'Hormone Resistin' is secreted primarily by adipose tissue in humans (and by macrophages in rodents). Its primary function is to: MCQ with Answer and Explanation

The 'Hormone Resistin' is secreted primarily by adipose tissue in humans (and by macrophages in rodents). Its primary function is to:
A. Enhance insulin sensitivity
B. Stimulate fat storage
C. Inhibit appetite
D. Antagonize insulin action, promoting insulin resistance and increasing hepatic glucose production
Answer: Option D
Solution (By JKSSB Mock Tests)
Resistin is a cysteine-rich peptide hormone secreted primarily by adipose tissue in humans (though in rodents, it is mainly secreted by macrophages). Its name is derived from its proposed role in 'resistance' to insulin. Its primary function is to antagonize the action of insulin, thereby promoting insulin resistance. It does this by increasing hepatic glucose production (gluconeogenesis) and impairing glucose uptake by muscle and adipose tissue. Elevated levels of resistin are associated with obesity and type 2 diabetes, linking adiposity to insulin resistance.

Discuss this Question (0)

No comments yet. Be the first to start the discussion!

Practice More Biology Questions

Question #1
The term used for organisms that can synthesize their own food from inorganic substances is:
A. Parasites
B. Autotrophs
C. Saprotrophs
D. Heterotrophs

Correct Answer: Option B


Explanation:
Autotrophs (self-feeders) include photoautotrophs (plants, algae, cyanobacteria) and chemoautotrophs (some bacteria). They produce organic matter from CO₂. Heterotrophs depend on others, saprotrophs decompose dead matter, parasites live on hosts.

This question belongs to: Science Biology
Question #2
Which sexually transmitted disease is caused by the bacterium Treponema pallidum?
A. Gonorrhea
B. Chlamydia
C. Syphilis
D. Genital herpes

Correct Answer: Option C


Explanation:
Syphilis is caused by the spirochete bacterium Treponema pallidum, typically transmitted through sexual contact. It progresses through primary, secondary, latent, and tertiary stages, potentially causing severe neurological and cardiovascular damage if untreated. Gonorrhea is by Neisseria gonorrhoeae, herpes by HSV, chlamydia by Chlamydia trachomatis. Penicillin is an effective treatment.

This question belongs to: Science Biology
Question #3
In genetics, the 'Lac operon' is an example of a(n):
A. Attenuated operon
B. Inducible operon
C. Repressible operon
D. Constitutive operon

Correct Answer: Option B


Explanation:
The lac operon in E. coli is a classic example of an inducible operon. It is normally 'off' (repressed) because the lac repressor protein, produced by the 'i' gene, binds to the operator, preventing transcription of the structural genes (z, y, a) needed for lactose metabolism. However, when lactose is present in the environment, it is converted to allolactose, which acts as an inducer. Allolactose binds to the repressor, changing its shape and preventing it from binding to the operator, thus 'inducing' or allowing transcription to occur.

This question belongs to: Science Biology