The hormone secretin, released by the duodenal mucosa, primarily stimulates the pancreas to secrete: MCQ with Answer and Explanation

The hormone secretin, released by the duodenal mucosa, primarily stimulates the pancreas to secrete:
A. Insulin
B. Water and bicarbonate ions
C. Glucagon
D. Digestive enzymes
Answer: Option B
Solution (By JKSSB Mock Tests)
Secretin is a peptide hormone released by the S cells of the duodenal mucosa in response to acidic chyme entering from the stomach. Its primary action is to stimulate the pancreatic ductal cells to secrete a large volume of water and bicarbonate ions. This alkaline juice neutralizes the acidic chyme, providing the optimal pH for pancreatic digestive enzymes to function. Cholecystokinin (CCK) stimulates enzyme secretion.

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