The scientist who demonstrated that DNA replication is semi-conservative was: MCQ with Answer and Explanation

The scientist who demonstrated that DNA replication is semi-conservative was:
A. Meselson and Stahl
B. Watson and Crick
C. Chargaff
D. Hershey and Chase
Answer: Option A
Solution (By JKSSB Mock Tests)
Matthew Meselson and Franklin Stahl, in 1958, used density gradient centrifugation of E. coli grown in N¹⁵ medium to prove that DNA replication is semi-conservative: each new DNA molecule consists of one old and one new strand. Watson and Crick proposed the double helix, Hershey-Chase confirmed DNA as genetic material, Chargaff formulated base pair rules.

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Practice More Biology Questions

Question #1
The vitamin that is part of coenzyme A and is involved in acyl group transfer is:
A. Riboflavin
B. Pantothenic acid
C. Thiamine
D. Biotin

Correct Answer: Option B


Explanation:
Pantothenic acid (vitamin B₅) is a component of coenzyme A (CoA), essential for the Krebs cycle and fatty acid metabolism. Thiamine is TPP, riboflavin FAD, biotin for carboxylation.

This question belongs to: Science Biology
Question #2
The scientist who proposed the 'one gene-one enzyme' hypothesis using Neurospora crassa was:
A. Beadle and Tatum
B. Watson and Crick
C. Mendel
D. Morgan

Correct Answer: Option A


Explanation:
George Beadle and Edward Tatum irradiated Neurospora crassa and showed that mutations in specific genes caused defects in specific enzymes, leading to the one gene-one enzyme concept. Watson and Crick discovered DNA structure, Mendel laws of inheritance, Morgan chromosome theory.

This question belongs to: Science Biology
Question #3
Consider statements about ecology: 1. Producers form the first trophic level. 2. Energy flow in an ecosystem is unidirectional. 3. The pyramid of energy can be inverted. Which are correct?
A. 1 and 3 only
B. 2 and 3 only
C. 1, 2 and 3
D. 1 and 2 only

Correct Answer: Option D


Explanation:
Green plants (producers) always occupy the first trophic level in a food chain. Energy flow is unidirectional, moving from the sun to producers and then to consumers, never returning to the sun. Due to the 10% law of energy transfer, the pyramid of energy is always upright and can never be inverted. Thus, statements 1 and 2 are correct.

This question belongs to: Science Biology