The scientist who proposed the 'lock and key' model of enzyme action was: MCQ with Answer and Explanation

The scientist who proposed the 'lock and key' model of enzyme action was:
A. Daniel Koshland
B. Emil Fischer
C. Leonor Michaelis
D. Maud Menten
Answer: Option B
Solution (By JKSSB Mock Tests)
Emil Fischer proposed the lock-and-key model in 1894, suggesting that the enzyme's active site is exactly complementary to the substrate, like a key fits a lock. Koshland later proposed the induced fit model, which is more widely accepted. Michaelis and Menten developed enzyme kinetics equations.

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Practice More Biology Questions

Question #1
The process of formation of blood cells is called:
A. Hemolysis
B. Hematopoiesis
C. Hematuria
D. Hemostasis

Correct Answer: Option B


Explanation:
Hematopoiesis is the production of formed elements of blood (red cells, white cells, platelets) from hematopoietic stem cells in the bone marrow. Hemolysis is RBC destruction, hemostasis is stopping bleeding, hematuria is blood in urine. Erythropoietin stimulates RBC production.

This question belongs to: Science Biology
Question #2
The process of removal of metabolic wastes from the body is called:
A. Circulation
B. Respiration
C. Excretion
D. Digestion

Correct Answer: Option C


Explanation:
Excretion is the elimination of nitrogenous waste products (urea, uric acid, ammonia) and other metabolic wastes from the body, primarily by the kidneys. Digestion is breakdown of food, circulation is transport, respiration is gas exchange and energy release. Excretion maintains homeostasis of body fluids and prevents toxic accumulation.

This question belongs to: Science Biology
Question #3
Consider statements about scientists: 1. Robert Hooke coined the term 'cell'. 2. Antonie van Leeuwenhoek discovered living microorganisms. 3. Charles Darwin proposed the cell theory. Which are correct?
A. 1 and 2 only
B. 1 and 3 only
C. 1, 2 and 3
D. 2 and 3 only

Correct Answer: Option A


Explanation:
Robert Hooke, in his 1665 book 'Micrographia', described observing dead cork tissue under a microscope and coined the term 'cell' for the small, box-like compartments he saw. Antonie van Leeuwenhoek, using his superior handcrafted single-lens microscopes in the 1670s, was the first person to observe and describe living, single-celled microorganisms, which he called 'animalcules'. Charles Darwin proposed the theory of evolution by natural selection; the cell theory was proposed by Schleiden and Schwann. Thus, statements 1 and 2 are correct.

This question belongs to: Science Biology