Which organelle is primarily responsible for the detoxification of lipid-soluble drugs and toxins in liver cells? MCQ with Answer and Explanation

Which organelle is primarily responsible for the detoxification of lipid-soluble drugs and toxins in liver cells?
A. Rough Endoplasmic Reticulum
B. Smooth Endoplasmic Reticulum
C. Golgi Apparatus
D. Lysosome
Answer: Option B
Solution (By JKSSB Mock Tests)
The Smooth Endoplasmic Reticulum (SER) in liver hepatocytes contains enzymes like cytochrome P450 that detoxify lipid-soluble drugs, metabolic waste, and toxins by making them water-soluble for excretion. Rough ER is involved in protein synthesis, the Golgi apparatus in packaging and secretion, and lysosomes in intracellular digestion. Exam tip: SER is abundant in liver and adrenal cortex cells.

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Question #1
Sericulture is the rearing of which insect for the production of silk?
A. Silkworm (Bombyx mori)
B. Prawn
C. Honeybee
D. Lac insect

Correct Answer: Option A


Explanation:
Sericulture is the process of rearing silkworms (primarily Bombyx mori) for the production of silk. The silkworm feeds on mulberry leaves (Morus alba) and spins a continuous filament of silk protein (fibroin) to form a cocoon around itself during its pupal stage. The cocoons are then boiled to kill the pupa and unwind the silk filament for textile production.

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Question #2
The term 'biological magnification' refers to:
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B. The increasing concentration of non-biodegradable toxic substances in organisms at higher trophic levels
C. The increase in biodiversity in a climax community
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Correct Answer: Option B


Explanation:
Biological magnification (or biomagnification) is the process where the concentration of persistent, non-biodegradable toxic substances (like DDT, mercury, or PCBs) increases progressively at each successive trophic level in a food chain. Because these substances are not metabolized or excreted, they accumulate in the tissues of organisms. Top predators end up with the highest, often lethal, concentrations of these toxins.

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Question #3
The movement of molecules from a region of higher concentration to a region of lower concentration without a membrane is:
A. Facilitated diffusion
B. Osmosis
C. Active transport
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Correct Answer: Option D


Explanation:
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This question belongs to: Science Biology