In the process of blood clotting, the enzyme 'thrombin' is formed from its inactive precursor 'prothrombin' in the presence of: MCQ with Answer and Explanation

In the process of blood clotting, the enzyme 'thrombin' is formed from its inactive precursor 'prothrombin' in the presence of:
A. Heparin and potassium
B. Thromboplastin and calcium ions
C. Fibrinogen and calcium
D. Plasmin and sodium
Answer: Option B
Solution (By JKSSB Mock Tests)
Blood clotting (coagulation) is a cascade of enzymatic reactions. When tissue is damaged, it releases thromboplastin (tissue factor). In the presence of calcium ions (Ca2+), thromboplastin activates the conversion of the inactive plasma protein prothrombin (synthesized in the liver with the help of Vitamin K) into the active enzyme thrombin. Thrombin then catalyzes the conversion of soluble fibrinogen into insoluble fibrin threads, forming the clot mesh.

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