The corpus luteum secretes which hormone that maintains pregnancy in early stages?
A. Progesterone
B. Estrogen
C. Luteinizing hormone
D. Human chorionic gonadotropin (hCG)
Answer: Option A
Solution (By JKSSB Mock Tests)
The corpus luteum, formed from the ruptured follicle after ovulation, secretes progesterone (and some estrogen) which prepares the endometrium for implantation and maintains early pregnancy until the placenta takes over (around 8-10 weeks). hCG, produced by the placenta, maintains the corpus luteum. Progesterone is crucial for maintaining the uterine lining.
Explanation:
The Philadelphia chromosome is a specific genetic abnormality found in the bone marrow cells of most patients with Chronic Myelogenous Leukemia (CML). It is formed by a reciprocal translocation between the long arms of chromosome 9 and chromosome 22, denoted as t(9;22). This translocation fuses the BCR gene on chromosome 22 with the ABL1 gene on chromosome 9, creating a mutant BCR-ABL1 fusion protein with constitutive tyrosine kinase activity, driving uncontrolled cell division.
Explanation:
Glucagon, from the pancreatic alpha cells, raises blood glucose by stimulating glycogenolysis and gluconeogenesis in the liver. Cortisol and growth hormone also raise blood glucose but glucagon is the primary direct antagonist of insulin. Thyroxine increases metabolic rate. The balance between insulin (hypoglycemic) and glucagon (hyperglycemic) maintains glucose homeostasis.
Explanation:
Thyroid-stimulating hormone (TSH) from the anterior pituitary binds to thyroid follicular cells, stimulating the release of T₃ and T₄.
No comments yet. Be the first to start the discussion!