The disease 'pellagra' is caused by the deficiency of: MCQ with Answer and Explanation

The disease 'pellagra' is caused by the deficiency of:
A. Vitamin B₆ (Pyridoxine)
B. Vitamin B₂ (Riboflavin)
C. Vitamin B₃ (Niacin)
D. Vitamin B₁ (Thiamine)
Answer: Option C
Solution (By JKSSB Mock Tests)
Pellagra, characterized by dermatitis, diarrhea, and dementia (3 Ds), is caused by a deficiency of niacin (vitamin B₃) or its precursor tryptophan. It is common in populations with corn-based diets lacking tryptophan. Beriberi is due to B₁ deficiency, cheilosis to B₂, peripheral neuropathy to B₆. Niacin is a component of coenzymes NAD and NADP.

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Question #1
Which of the following is NOT a type of plastid?
A. Peroxisome
B. Chloroplast
C. Chromoplast
D. Leucoplast

Correct Answer: Option A


Explanation:
Peroxisomes are single-membrane organelles involved in oxidative reactions, not plastids. Plastids (chloroplasts, chromoplasts, leucoplasts) are double-membrane organelles found in plants and algae, involved in photosynthesis, storage, and pigmentation. Chloroplasts contain chlorophyll, chromoplasts carotenoids, leucoplasts are colorless storage plastids.

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Question #2
The structural and functional unit of heredity is the:
A. DNA
B. Gene
C. Nucleotide
D. Chromosome

Correct Answer: Option B


Explanation:
A gene is a segment of DNA that codes for a functional product (protein or RNA) and is the basic unit of heredity. It determines traits. Chromosomes are structures containing many genes. DNA is the genetic material, and nucleotides are the building blocks. Genes are passed from parents to offspring.

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Question #3
Consider statements about human immunity: 1. B-lymphocytes produce antibodies. 2. T-lymphocytes are involved in cell-mediated immunity. 3. Vaccines cure active viral infections. Which are correct?
A. 1 and 2 only
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C. 2 and 3 only
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Correct Answer: Option A


Explanation:
B-lymphocytes (B cells) differentiate into plasma cells that secrete antibodies, providing humoral immunity. T-lymphocytes (T cells) are responsible for cell-mediated immunity, directly attacking infected or cancerous cells. Vaccines are prophylactic; they stimulate the immune system to develop memory and prevent future infections, but they do not cure active, ongoing viral infections. Thus, statements 1 and 2 are correct.

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