The 'Hormone Fibroblast Growth Factor 21' (FGF21) is primarily produced by the liver in response to various metabolic stresses. Its primary function is to: MCQ with Answer and Explanation

Fibroblast Growth Factor 21 (FGF21) is a hormone primarily secreted by the liver (and to a lesser extent by adipose tissue and pancreas) in response to metabolic stresses like fasting, a high-carbohydrate diet, or mitochondrial dysfunction. Its primary functions are to regulate glucose and lipid metabolism. It improves insulin sensitivity, promotes the uptake of glucose by adipose tissue, stimulates the breakdown of fats (lipolysis) and ketogenesis in the liver, and reduces triglyceride levels. It is considered a 'starvation hormone' and a potential therapeutic target for metabolic diseases like diabetes and obesity.