The 'Hormone Melanocyte-Stimulating Hormone' (MSH) in humans is primarily derived from the cleavage of a larger precursor protein called: MCQ with Answer and Explanation

In humans, the intermediate lobe of the pituitary is rudimentary, and most Melanocyte-Stimulating Hormone (MSH) is produced in the anterior lobe (pars distalis). It is not synthesized as a separate hormone but is derived from the proteolytic cleavage of a large precursor polypeptide called pro-opiomelanocortin (POMC). POMC is cleaved to produce several biologically active peptides, including Adrenocorticotropic Hormone (ACTH), beta-lipotropin, beta-endorphin, and various forms of MSH (alpha, beta, gamma).