The 'Hormone Melanocyte-Stimulating Hormone' (MSH) in humans is primarily derived from the cleavage of a larger precursor protein called: MCQ with Answer and Explanation

The 'Hormone Melanocyte-Stimulating Hormone' (MSH) in humans is primarily derived from the cleavage of a larger precursor protein called:
A. Pro-opiomelanocortin (POMC)
B. Prorenin
C. Prothrombin
D. Proinsulin
Answer: Option A
Solution (By JKSSB Mock Tests)
In humans, the intermediate lobe of the pituitary is rudimentary, and most Melanocyte-Stimulating Hormone (MSH) is produced in the anterior lobe (pars distalis). It is not synthesized as a separate hormone but is derived from the proteolytic cleavage of a large precursor polypeptide called pro-opiomelanocortin (POMC). POMC is cleaved to produce several biologically active peptides, including Adrenocorticotropic Hormone (ACTH), beta-lipotropin, beta-endorphin, and various forms of MSH (alpha, beta, gamma).

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Practice More Biology Questions

Question #1
The antibiotic penicillin is obtained from:
A. Fungus
B. Protozoa
C. Algae
D. Bacteria

Correct Answer: Option A


Explanation:
Penicillin is derived from the fungus Penicillium chrysogenum (formerly P. notatum). Alexander Fleming discovered it in 1928.

This question belongs to: Science Biology
Question #2
Consider statements about vitamins: 1. Vitamin A deficiency causes night blindness. 2. Vitamin B1 deficiency causes beriberi. 3. Vitamin C deficiency causes rickets. Which are correct?
A. 1 and 2 only
B. 1, 2 and 3
C. 2 and 3 only
D. 1 and 3 only

Correct Answer: Option A


Explanation:
Vitamin A is essential for the synthesis of rhodopsin, a visual pigment; its deficiency leads to night blindness, the inability to see in low light. Vitamin B1 (thiamine) is crucial for carbohydrate metabolism; its deficiency causes beriberi, characterized by nerve and heart dysfunction. Vitamin C deficiency causes scurvy, characterized by bleeding gums and poor wound healing; rickets is caused by a deficiency of Vitamin D, leading to soft, weak bones in children. Thus, statements 1 and 2 are correct.

This question belongs to: Science Biology
Question #3
The part of the human ear that converts sound vibrations into neural signals is the:
A. Eardrum
B. Auditory nerve
C. Cochlea
D. Ossicles

Correct Answer: Option C


Explanation:
The cochlea, a spiral-shaped organ in the inner ear, contains the organ of Corti with hair cells that transduce mechanical vibrations into electrical impulses. The eardrum and ossicles conduct sound to the cochlea. The auditory nerve transmits impulses to the brain. Thus, transduction occurs in the cochlea.

This question belongs to: Science Biology