Which enzyme is responsible for unwinding the DNA double helix during replication?

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Helicase unwinds the DNA helix at the replication fork by breaking hydrogen bonds between base pairs. DNA polymerase adds nucleotides, ligase seals Okazaki fragments, primase synthesizes RNA primer. This coordinated action ensures accurate semi-conservative replication. Without helicase, the strands would not separate. Energy for unwinding comes from ATP hydrolysis.

Which enzyme is responsible for unwinding the DNA double helix during replication? MCQ with Answer and Explanation

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