Pernicious anemia is caused by the deficiency of: MCQ with Answer and Explanation

Pernicious anemia is caused by the deficiency of:
A. Folic acid
B. Vitamin B12
C. Vitamin C
D. Iron
Answer: Option B
Solution (By JKSSB Mock Tests)
Pernicious anemia is a specific type of megaloblastic anemia caused by the inability to absorb Vitamin B12 (Cobalamin) due to a lack of intrinsic factor, a protein secreted by the stomach. Vitamin B12 is essential for red blood cell formation and neurological function. Its deficiency leads to the production of large, immature, and dysfunctional red blood cells.

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Practice More Biology Questions

Question #1
The pigment that gives red algae their characteristic color is:
A. Phycoerythrin
B. Chlorophyll a
C. Fucoxanthin
D. Phycocyanin

Correct Answer: Option A


Explanation:
Phycoerythrin is a red phycobiliprotein that masks chlorophyll in red algae (Rhodophyta). Phycocyanin is blue in cyanobacteria, fucoxanthin brown in brown algae. These accessory pigments allow light absorption at depths.

This question belongs to: Science Biology
Question #2
Consider statements about biotechnology: 1. Genetic engineering can create transgenic organisms. 2. Cloning produces genetically identical copies. 3. Tissue culture is used for animal cloning only. Which are correct?
A. 1, 2 and 3
B. 1 and 2 only
C. 2 and 3 only
D. 1 and 3 only

Correct Answer: Option B


Explanation:
Genetic engineering involves the direct manipulation of an organism's genome, often used to create transgenic organisms that contain foreign DNA (transgenes) for desired traits. Cloning is the process of producing genetically identical copies of a biological entity, ranging from genes to entire organisms. Tissue culture (micropropagation) is widely used for the rapid, large-scale propagation of plants from small explants in a sterile medium; it is not exclusively or primarily used for animal cloning. Thus, statements 1 and 2 are correct.

This question belongs to: Science Biology
Question #3
The enzyme telomerase is highly active in which type of cells?
A. Mature red blood cells
B. Somatic cells
C. Stem cells and cancer cells
D. Neurons

Correct Answer: Option C


Explanation:
Telomerase is a ribonucleoprotein enzyme that adds repetitive nucleotide sequences to the ends of chromosomes (telomeres), preventing them from shortening during DNA replication. It is highly active in germ cells, stem cells, and most cancer cells, granting them replicative immortality. In most normal somatic cells, telomerase is inactive, leading to gradual telomere shortening and cellular aging.

This question belongs to: Science Biology